Domaine Jean-Pierre Guyon is one of the most outstanding domaine in Vosne-Romanée. Since 2012 the domaine has been certified organic. Nowadays, Domaine Jean-Pierre Guyon is run by high-pedigree winemaker Jean-Pierre Guyon.

Top wines of the domaine are: Echézeaux Grand Cru, Clos de Vougeot Grand Cru. Echézeaux Grand Cru 2020 scored 95-97, Echézeaux Grand Cru 2019 scored 95-97, and Clos de Vougeot Grand Cru 2019 scored 94-96 by the Wine Advocate. Robert Parker comments on Echézeaux Grand Cru 2020: “The 2020 Echézeaux Grand Cru seems likely to surpass its 2019 counterpart. Bursting with aromas of plums and raspberries mingled with notes of rose petal, incense, sweet spices, peonies and orange rind, it's full-bodied, multidimensional and textural, with a velvety attack, terrific concentration and a long, expansive finish. Deep and complete, with exquisitely refined tannins”.

Jean-Pierre Guyon is a current owner of the domaine, who footsteps his predecessors. He is exclusively accurate in his vineyard work.

Since 2012 the domaine has been certified as organic by Ecocert. Jean-Pierre Guyon uses only ripe grapes, as the whole bunches are fermented. When fermentation is complete, the free-run juice is drawn off and the must is pressed.

Wines are matured for 12 months in barrels, then racked into tanks for a final few months' maturation.